It's been a long time since Big Pharma has delivered anything close to a cure for anything.
It seems like all the drugs that come out these days are some kind of "treatment" designed to keep us dependent on Big Pharma for the rest of our lives, so a drug that can wipe out high cholesterol in one shot is kind of big news.
Lipoprotein(a) is a type of cholesterol that most tests are not designed to detect because there hasn't been any kind of treatment for it, and diet and exercise don't touch it.
It's the type of cholesterol that you only hear about when a person who is in great shape, eats right, and goes running every day, suddenly keels over from a heart attack in their 40s.
And 64 million people in the U.S. have issues with it.
The new drug called lepidisiran, that just passed its phase 2 clinical tests, blocks the body's natural mRNA from creating the harmful cholesterol, and blew the placebos out of the water, wiping out nearly 94% of Lipoprotein(a) in one shot.
'This is a major source of cardiovascular morbidity and mortality,' said Dr. Steven Nissen, chief academic officer of the Heart, Vascular & Thoracic Institute at the Cleveland Clinic and lead researcher of the lepidisiran trial. 'We have never been able to treat lipoprotein(a) until now,' he said.
After one year, the patients' levels were still at an 89% reduction, so the effects do seem to wear off over time, but it's still a remarkable advancement.
Millions of Americans may be able to enjoy breakfast foods guilt-free again.
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